The article provides insights into IVF treatment at the renowned Instituto Bernabeu clinic. The image showcases the clinic's exterior.

Instituto Bernabeu

IVF package cost:
Egg donation cost:
€6,500 - €7,000

Table of Contents

IVF Treatment at Instituto Bernabeu—Availability

IVF at Instituto Bernabeu - restrictions
Woman maximum age50
Single womanAllowed
Same sex female couplesAllowed
HIV (female)Allowed
HIV (male)Allowed
HCV / HBV (female)Allowed
HCV / HBV (male)Allowed

Introducing Instituto Bernabeu—Cutting-Edge Expertise

Instituto Bernabeu was founded in 1985 and has since become one of the leading infertility clinics in all of Spain, with a total of 8 fertility clinics, located in Alicante, Madrid (2 clinics in Madrid: Ayala Street and Velazquez Street), Venice (Italy), Palma de Mallorca, Cartagena, Albacete, Elche and Benidorm. Instituto Bernabeu commits to quality of care to ensure that all of their patients receive only the very best care. Thanks to this commitment to quality they have been on the receiving end of being awarded multiple certificates based around quality and excellence in care. Some of their certificates are:

  • ISO 9001
  • ISO 14001
  • SEP, for excellence in private health
  • EFQM, European Foundation for Quality Management
  • QH Quality Healthcare
  • UNE179007.

These are just some of the certificates for quality in care that they have received, as well as many others, showing that they have a true commitment when it comes to the quality of care that you will receive.

It is not just work in their clinic that they do, they collaborate with both the University of Alicante and the Miguel Hernández University of Elche, in order to assist in the advancement of infertility treatment, to ensure that the treatment techniques and medical equipment used are always at the forefront of medical science. This has helped them become a highly advanced clinic that is able to implement highly successful treatment plans that have been designed, and personalised, specifically for women who have had repeated implantation failure, and recurrent miscarriages, due to a variety of reasons such as obesity, low ovarian reserve, endometriosis, and more. This is why they are at the forefront of infertility treatment.

With a commitment to ongoing research and the incorporation of the latest advancements in reproductive medicine, Instituto Bernabeu remains at the forefront of addressing embryo implantation failures, providing hope and solutions for couples on their journey to parenthood.

If you have been diagnosed with low ovarian reserve or low ovarian response, Instituto Bernabeu is the right place to go for further tests and treatment. The clinic has its own Low Ovarian Reserve Unit where cases like this are successfully treated. Dr. Ana Fuentes, head of the Low Ovarian Reserve Unit at the Bernabeu Institute, explains how PRP, platelet-rich plasma, a technique for ovarian reactivation (rejuvenation) works.

Instituto Bernabeu has quite the history as well, with a multitude of firsts that show that when it comes to infertility treatment, they know their stuff. Some of their achievements include:

  • World’s first birth of a child free of hereditary blindness.
  • First IVF pregnancy in the Valencian community.
  • World’s first birth of a child free of Marfan Syndrome, whilst applying the MDA technique.
  • The first and only case in Spain of a pregnancy achieved without the use of spermatids.
  • The first clinic in all of Europe to offer a childbirth and pregnancy guarantee, or a 100% refund.

It is not just firsts that the clinic is known for, but it’s multiple awards for excellence in multiple areas. In fact, in 2021 they won the national EMB-ASEBIR award, which is the greatest award in Spain you can be given when it comes to assisted reproduction. This isn’t the first time they have won this highly prestigious award either, as they won it in both 2009 and 2013. Winning this award just once is impressive, but to win it 3 times in 12 years is even more so.

During this very impressive history they have performed over 48,000 treatments, which has resulted in over 20,000 births for patients from over 137 countries, showing that, despite the clinic being located in Spain, they are truly an international clinic.


Instituto Bernabeu staff

Experience and Medical Staff at Instituto Bernabeu

Heading up the Instituto Bernabeu is dr Rafael Bernabeu, a man with a vast amount of experience, having graduated in 1980 from medical school at the University of Valencia, with an honours degree in Medicine and Surgery. Since 1984 he has been a specialist in Gynaecology and Obstetrics, whilst also undergoing training in many prestigious universities around the world, such as Cornell University and John Hopkins University, the latter of which is known as one of the top research universities in the entire world.

He has authored over 120 national and international articles, as well as over 400 research papers, and regularly speaks at conferences, whilst also being the spokesperson for the SEF (Spanish Fertility Society). With such a highly trained and qualified person in charge, it is no wonder that Instituto Bernabeu is so highly regarded.

Dr Rafael Bernabeu
Dr Rafael Bernabeu

But what is a leader without a team, and Instituto Bernabeu has a very large team spread across all of its clinics. With 30 doctors, 17 embryologists 4 of whom are certified ESHRE accredited embryologists, and a countless number of specialists, they have a team with a massive amount of experience in treating infertility, and the qualifications to go along with it. Because they have such a large number of staff, there is sure to be someone who speaks the same language as you, so you will always feel comfortable knowing someone will understand you and that there will be no language barrier.

Part of the staff includes Personal Care Assistants, who are there for you during your entire treatment, from the very beginning to the very end. They will always be at your disposal, to ensure that any questions you have at any point are answered and that any needs are met. You will be able to speak to them no matter where you are, whether at the clinic itself, wandering around the city the clinic is located in, or at home, you will always be able to speak to them, because they are there for you.

From the initial consultation to the final stages of the process, Instituto Bernabeu’s patient-centric approach ensures that each individual’s unique needs and concerns are addressed.

Due to their wealth of experience and advanced techniques, they can offer their services to a wide variety of people. They can treat women who are seen as older, all the way up to the age of 50, whereas a lot of other clinics have an age limit of 48. Whether you are a woman who is married to a man or a woman, single, or transgender, you have treatment options available to you at Instituto Bernabeu thanks to the many treatments that are available.

IVF Costs at Instituto Bernabeu

The cost of treatment, when it comes to treating infertility, isn’t always set in stone, as different patients have different needs, due to there being a multitude of reasons as to why you require treatment. Because of this, there are personalised treatment plans that are catered towards your needs, and as such, the cost will be different. So if you know someone who has undergone infertility treatment, with Instituto Bernabeu, and you wish to undergo treatment as well, you might find that you will pay less, or more, depending on your treatment needs.

As part of the treatment, you can be treated using your own eggs, or donor eggs, as well as sperm from your own partner, or a donor bank, of which Instituto Bernabeu has one of their own. Prices will be different depending on the route you need to take, in order to make your dream come true. The initial consultation for your visit will always be 140 Euros, regardless of your treatment needs. The most basic treatment is IUI which is intrauterine insemination – available at the cost of 1,000. You can also undergo IUI with donor sperm (AID) – this will cost you 1,500 Euros.

Basic IVF packages cost at Instituto Bernabeu
Intrauterine insemination (IUI)€1,000
Artificial insemination with donor (AID)€1,500
IVF with own eggs€5,000
Egg donation IVF€6,500 - €7,000
Embryo donationfrom €4,000
Egg freezing€2,000 (2-year storage included)
Sperm donationfrom €5,500
ROPA€5,500 - €16,450
Surrogacynot available

IVF treatment costs are:

  • IVF treatment with egg donation – 7,500 Euros
  • IVF treatment with donor eggs – 5,000 Euros per cycle.

Sometimes additional testing is required on the embryos, the tests, which are pre-implantation tests will cost 550 Euros, and 400 Euros per additional embryo.

As we stated above the clinic accepts women who are in relationships with women, and transgender couples, who wish to have a child. For this, there is a treatment called ROPA (Reception of Oocytes from the Partner aka Reciprocal IVF). The costs for this treatment are:

  • Standard ROPA – 5,500 Euros
  • ROPA Guarantee program – 16,450 Euros.

The ROPA guarantee program promises that you will receive your money back if you do not achieve pregnancy and birth over 3 IVF cycles. You are required to fulfil certain requirements in order to qualify, so you will need to speak with your specialist to see if you do.

IVF Treatments Add ons and Other Costs

Other IVF techniques costs at Instituto Bernabeu
Medical consultation (doctor)from €140
Donor sperm€500
Sperm freezing€500
Embryo Monitoring (e.g. Embryoscope)included in treatment price
Blastocyst cultureincluded in treatment price
PGT-A / PGS genetic embryo testingfrom €550
Embryo freezing and storage for 1 year€300
FET - Frozen Embryo Transfer€1,500

IVF Refund Guarantee Package

There are two more pregnancy and childbirth guarantee packages available, both of which offer a 100% refund if pregnancy and childbirth is not achieved, over 3 IVF cycles.

  • IVF/ICSI and Egg Donation – 16,950 Euros
  • IVF with Egg Donation – 17,950 Euros.

Refund Package (Money back guarantee):

Pregnancy and Childbirth Guarantee FIV/ICSI + Egg donation Programme - 16950 EUR
Refund is guaranteed if the program does not end with the desired result.
Refund amount: 100% if live birth is not achieved
No. of IVF cycles included: 3 complete cycle(s)
Program qualification is necessary. Please ask the clinic for details.

Pregnancy and Childbirth Guarantee Egg donation Programme - 17950 EUR
Refund is guaranteed if the program does not end with the desired result.
Refund amount: 100% if live birth is not achieved
No. of IVF cycles included: 3 complete cycle(s)
Program qualification is necessary. Please ask the clinic for details.

IVF Success Rates at Instituto Bernabeu

IVF success rates are one of the indicators as to whether or not an infertility clinic is worth going to, and Instituto Bernabeu sees above average success rates compared with other clinics in Europe. Their clinical pregnancy success rate for IVF with donor eggs per embryo transfer were 50.3% and the clinical pregnancy success rate for IVF with own eggs per embryo transfer was 49%. Then, IVF with own eggs clinical pregnancy success rate per embryo transfer broken down to patients’ age looks as follows:

  • Women aged under 35 – 54%
  • Women aged 35-40 – 43.3%
  • Women aged over 40 – 15.1%.

Their success rates with embryos are:

  • IVF using frozen embryos – 38.1%
  • IVF using donated embryos – 40.2%

All of the above success rates are based on achieving a clinical pregnancy and are measured per single embryo transfer, excluding the consecutive frozen transfers.

Instituto Bernabeu—Location

The main clinic for Instituto Bernabeu is located in Alicante, a gorgeous city situated right next to the sea, with beautiful water to gaze at in wonder. If you do decide to go to the main clinic in Alicante, then you can combine your infertility treatment with a wonderful holiday in a truly beautiful city, that is lined with amazing beaches, and many things to do either on the beach or in the city.

The clinic is located 1 km from the city centre and has a chauffeur pickup that will pick you up at the airport once you land and take you back when you are ready to return. On-site they have 9 en-suite recovery rooms so that your recovery goes as smoothly as possible. When it comes to hotels and the like, Instituto Bernabeu will provide you with all of the necessary information, to help facilitate your journey and make it as easy as possible.

Instituto Bernabeu - FAQ
What is the average cost of IVF with your own eggs at Instituto Bernabeu?

The average cost of IVF treatment with your own eggs at Instituto Bernabeu is 5,000 Euros. However, this doesn’t include the medication that will be needed throughout the treatment, but this can be bought at a pharmacy in your own country, or at a pharmacy in Spain. The average cost of this medication is 1,200 Euros, although the cost may vary depending on what medication your specialist believes you will require for the treatment. What is included in the 5,000 Euros cost is all of the laboratory costs, as well as the first transfer of the first embryo.

What are the costs of popular IVF add-ons at Instituto Bernabeu?

One of the more popular add-ons that patients ask for at Instituto Bernabeu is PGD testing, which is Preimplantation Genetic Diagnosis, and the cost for this is 550 Euros for the first embryo, and 400 Euros for each additional embryo you would like tested. PGD is a test that is performed on the embryo whereby the cells are examined before implantation to ensure that it has the correct number of chromosomes and contains no genetic defects that can cause miscarriage, an unhealthy child and any serious illnesses that can be caused by the abnormalities in the chromosomes.

Other popular add-ons that you may opt for include embryo freezing. For vitrification and freezing of your embryos you will be expected to pay 500 Euros, no matter how many embryos you have frozen. The reason you may need to freeze any embryos is that you have some left over from your treatment and may wish to have another child in the future at some point.

What is the average cost of the egg donation cycle at Instituto Bernabeu?

The average cost of treatment with egg donation at Instituto Bernabeu is 6,500 Euros, although this does not include the medication that you will also require. The cost for the medication for your egg donor will be around 1,000 Euros, whilst the cost for the medication for you will be between 400 and 500 Euros, and will depend on what medication is required and prescribed by your doctor. The medication for you can be bought either in Spain or in your own country at a pharmacy of your choosing.

Included in the cost of egg donation treatment are all of the tests and screening for your donor, as well as any necessary scans, endometrium preparation and all of your scans until the transfer of the first embryo.

What kind of egg donor ethnicities are available at Instituto Bernabeu?

The Instituto Bernabeu has a large egg donor database so they have access to all ethnicities, with approximately 1,000 women willing to donate. If you are looking for East or South Asian eggs then there can sometimes be a little shortage, but with most other ethnicities they should have less trouble. Thanks to their large database you shouldn’t have to worry about waiting too long for your eggs.

Egg donors with the clinic face strict requirements in order to be a donor, with age and health being the main factors in becoming one. Donors are all between 18 and 33, and this is to ensure that the eggs are as healthy and fertile as possible, because this is very important to the success of the treatment. They must also be in good physical and mental health and to make sure of this they will undergo psychological testing as well as physical testing. As part of this testing they will be checked for infectious diseases and hereditary diseases, so that nothing can be transmitted to the embryo. The clinic will also ensure that the family history and personal history of the patient is looked at to determine if they are fit to be a donor. Further testing will be performed to ensure there are no chromosomal and genetic abnormalities. Thanks to this testing they are able to look at the genes and ensure that over 600 recessive diseases and over 3,000 hereditary diseases have no chance of passing to your child. With this testing and the requirements set out you can be sure to receive only healthy and fertile embryos. Egg donation is anonymous so you won’t be able to know who your donor is, but the clinic will choose the best donor for you.

What is the cost of PGT-A and how should it be calculated with IVF programs at Instituto Bernabeu?

The cost of PGT-A testing with Instituto Bernabeu is 550 for the first embryo you wish to have analysed, and 400 Euros for each additional embryo, so if you choose to have three embryos analysed you will be expected to pay 1,350 Euros. Regardless of the treatment you are undergoing, the cost for PGT-A testing will remain the same, so you will not have to pay more or less with a different treatment.

PGT-A is Preimplantation Genetic Testing, and as the name suggests it is testing that is performed prior to the implantation of the embryos that are being used in your treatment. It looks at the chromosomes in your embryo to determine whether or not there are any abnormalities present that will cause genetic defects or cause problems during the development of the foetus. Being able to test for this allows the clinic to ensure that only embryos without abnormalities and the correct number of chromosomes are implanted.

PGT-A testing is a relatively harmless procedure and has no effect on the mother as the test is performed on the embryos themselves.

What is the cost of donor sperm from the bank at Instituto Bernabeu?

The cost of donor sperm with Instituto Bernabeu is 500 Euros, and this cost is for every treatment the clinic has that will require sperm donation. So whether you are having treatment with your own eggs, donor eggs, or any other, if you require donor sperm the cost is the same.

When it comes to the donor ethnicities the clinic has access to most, although South Asian is a little more difficult to get, with East Asian having more availability. The other ethnicities are more available so you should have little to no waiting time should you choose.

All donors with the clinic are tested and have to meet specific requirements in order to donate, as per Spanish law. Some of these requirements include being between the ages of 18 and 35, not suffering from any STIs or genetic diseases, and being physically and psychologically healthy. In order to discover this they undergo testing whereby their sperm is tested to ensure it is healthy and fertile enough to be used in treatment, and they undergo psychological testing to ensure that they are of sound mind and understand what donating sperm really means. They will also undergo a blood test to test for STIs and genetic diseases which may pass down through their sperm if they have any in their family history, of which is also checked, as the clinic wishes to rule out anything passing on to your child. Thanks to all of the testing performed by the clinic you can be sure that the sperm you receive is the very best.

All donors with the clinic will remain anonymous so you will not be able to know who they are and they will not know of any children born as a result of their donation.

What is the average cost of the ROPA (IVF for same-sex female couples) cycle at Instituto Bernabeu?

The average cost of ROPA treatment with Instituto Bernabeu is around 5,500 Euros. This cost includes 5,000 Euros for the IVF treatment and 500 Euros for the donor sperm that you will need. This does not include the medication that will be needed and this will cost around 1,200 Euros, and can be purchased at either a pharmacy in Spain or a pharmacy in your own country.

A sperm donor will be needed and luckily the clinic has a large sperm selection in their bank, and all of the donors have been thoroughly tested both physically and mentally, to ensure that the sperm you receive is the very best and will be both healthy and fertile. This way you will have a higher chance of success with your treatment.

What is the average cost of embryo donation at Instituto Bernabeu?

The cost of fertility treatment with embryo donation at Instituto Bernabeu is 4,000 Euros, but this does not include the medication, and this will cover you for one embryo transfer. The medication involved with this treatment must be bought separately and will cost around 400 to 500 Euros, and it can be purchased at a pharmacy in your own country or in Spain, where the clinic is located.

If you are looking at having PGT-A testing performed on the embryos in this treatment you will be unable to do so, as the embryos would need to be vitrified twice in order to perform this test for this treatment, and this has a chance of damaging the embryos. However, the donors that the clinic uses must meet strict requirements, and are tested to ensure that their donations are healthy, so further testing would not be required.

What is the average cost of egg freezing at Instituto Bernabeu?

The cost in order to freeze your eggs with Instituto Bernabeu is 2,000 Euros and this cost includes the preparation, any scans that you need and the maintenance and storage for the first two years. Any medication you need during this is a separate cost and can be purchased at a pharmacy for about 700 Euros. Once the initial two years have passed you will need to pay an annual maintenance fee in order to keep your eggs stored, the cost for this is 300 Euros per year.

With so many different reasons it shows that egg freezing is important to a lot of people, as when they are in a position in their life to have children they know they can have access to their own eggs, which are still as healthy and fertile as the day they were frozen.

What are the average costs of intrauterine insemination and donor sperm insemination at Instituto Bernabeu?

The cost of IUI (Intrauterine Insemination) with Instituto Bernabeu is 1,000 Euros, if you are using your partner’s sperm. If you require a donor there will be an additional fee of 500 Euros for IUI, making the total 1,500 Euros.

During IUI, the sperm that is to be inserted, whether it is your partner’s sperm or donor sperm, is put into a small vial that is attached to a catheter, which is then slowly inserted into the vagina and eventually into the uterus. The sperm sample is then pushed through into the uterus and the catheter removed. This way there is a higher chance of healthy and fertile sperm reaching the eggs. The procedure itself is relatively painless and most patients will only feel a slight pinch and/or some cramping. This treatment doesn’t last too long either as from the beginning, when you undergo ovarian stimulation, until the end only 12 to 14 days will have gone by, compared to some of the other treatments that take place over a minimum of over 30 days in some cases.

If you do require donor sperm then you can be sure that the sperm that you receive will be healthy and fertile as the clinic has access to a large sperm bank and all donors are tested thoroughly, both mentally and physically, to ensure that their sperm is the healthiest possible.

Who is the medical director and what is the doctor’s experience in IVF treatment at Instituto Bernabeu?

The medical director of Instituto Bernabeu is Dr. Rafael Bernabeu who likes to keep the clinic as a family clinic with members of his own family working at the clinic as well. He has over 40 years of experience in reproductive medicine and has been involved in a lot of important milestones in the IVF community during that time. In fact, Dr. Bernabeu achieved the first baby born from IVF treatment in the Valencian community, which occured in 1987. He was also responsible for the first pregnancy in Spain with the use of microinjecting spermatids in 1985, as well as the first baby in the world to be born free of hereditary blindness in 2004, and the first baby born free of Marfan Syndrome in 2006. These achievements show that Dr. Rafael Bernabeu is a truly accomplished and experienced specialist, and is definitely a man whom you can trust with your treatment.

As for the rest of the staff they are all very experienced in reproductive medicine, as well as being professional, and giving patients a very good experience thanks to how close they can become with them. Very often patients are left feeling satisfied after their experiences and treatment with the clinic. They also have a lot of patient coordinators working for them, who speak multiple different languages, including: Spanish, English, Portuguese, French, Italian, Russian, and many more. With so many different languages spoken you are sure to feel comfortable at the clinic knowing that you will be understood and not have to worry about any issues with communication.

Where is Instituto Bernabeu located and how easy can patients get there from the airport?

Instituto Bernabeu has clinics in Alicante, Madrid and Palma, that have international department, and also national clinics in Mallorca, Cartagena, Albacete, Elch, Benidorm and Venice, so if you wish to undergo treatment with Instituto Bernabeu you have your choice of locations.

The clinic in Madrid is located near the city centre and is only about 20 to 25 minutes by car from the Adolfo Suárez Madrid–Barajas Airport, and only 39 minutes if you decide to take the Madrid Metro instead. You will also have the option of taking a taxi as well, many of which can be found nearby. However, you are in luck as the clinic has their own pick-up service available to you so you will not need to worry about organising your own transport, and they will also assist you with finding accommodation, in order to make your journey easier.

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