How To Cope With IVF Failures – What Happens To Your Body?

The article explores what to do after failed IVF. The featured image depicts a woman examining a pregnancy test.

Improvements in assisted reproductive technology are continuously nudging up IVF success rates and these improvements are being replicated in treatment centers around the world. Whilst success rates are rising, the number of patients accessing IVF treatments is also increasing. A successful IVF cycle may not be achieved the first time which means that in real terms the number of IVF cycles being performed is increasing alongside the number of unsuccessful cycles.

Guaranteeing successful fertility treatment is not therefore a given. As someone who has experienced a failed IVF treatment cycle, as well as a cycle that ended in an early miscarriage, I know how devastating both outcomes can be.

Finally accepting that a natural pregnancy might not be possible and acknowledging that fertility treatment is required can be a torturous process. The prospect of potential months of preparation (physical and psychological) and the IVF attempt itself can be intimidating and with no guarantee of success it is no surprise that many who ride the rollercoaster of a fertility journey experience self-doubt, frustration, depression and anxiety.

In contrast to the minefield of information that exists on how to prepare for IVF treatment, there is very little to advise patients on how to deal with treatment failure or repeated implantation failure. Whilst many people who write about IVF failure tend to describe their initial devastation and sometimes their eventual triumph over it, very few actually write about the practical things they might have done to help them through that period of their lives.

You may be interested in reading: IVF success rates explained

Even though it is true that grief is a process that takes its own time, there are things that may help you to cope better with everyday life.

Some of the coping strategies I’ve outlined here are more relevant to those who do wish to pursue further IVF treatment, but others are applicable to everyone, regardless of the next steps.

The IVF Failure blame game

While some degree of anger is expected in the aftermath of an IVF failure try not to let it take over or it can be destructive.

To find out that my IVF cycle had failed and knowing that we had no frozen embryos with which to attempt a follow-up cycle, was unbelievably heartbreaking.

My immediate reaction was to find someone to blame. At first, I blamed the clinic, convinced it was their negligence somewhere along the line that had caused harm to our embryos. I reflected back on every conversation I had had with them, trying to find holes in their processes and signs of their incompetence.

Then, inevitably, I turned the blame on myself, analysing every single move I made during the cycle and wondering what it was that I did to stop my embryos from implanting. Being unable to conceive naturally had already been a harsh prospect to come to terms with, but being unable to get pregnant through IVF made me feel more inadequate and more of an IVF failure than ever before.

You may be interested in reading: Things We Wish We Could Tell Our Fertility Clinic

Focus on the follow-up appointment

In the first few days, and possibly weeks, following a failed cycle, you will fill feel energy drained; it can be difficult to contemplate another IVF cycle, especially a fresh one. The grief can be so overwhelming that it’s impossible to fathom putting yourself in such a situation again.

About six weeks after a failed cycle, when emotions have settled down a little, clinics will typically schedule a follow-up appointment with a physician to review the cycle and try to understand where it might have gone wrong.

Try to hold out for this appointment and avoid making any definite decisions until you have talked to your infertility specialist. You may find that there are changes that can be made to the protocols that might help your odds on a subsequent cycle.

There may also be further fertility investigations that can be done or new techniques that can be tried. However, if egg quality is the suspected cause of IVF failure, it is worth preparing for the possibility that treatment options that you had previously rejected, such as using donor eggs, may now be the best chance of success.

Sometimes, patients after several IVF failures are starting to think about looking for fertility clinics abroad which may be a good choice if they are aware of all pros and cons of going abroad for an IVF.

Understand why the failure of IVF occurred

Try not to leave your follow up appointment without ensuring you fully understand why your treatment may have failed. Many of the IVF patients I spoke to who experienced an unsuccessful cycle didn’t realise that there were signs throughout the cycle that their odds of success were low.
For example, if the fertilization rates were very low, or the quality of the embryos on transfer day was poor.

On our first cycle, my husband and I had a very low fertilization rate and didn’t make it to a day-five transfer.

However, we were so happy that we had an embryo to transfer that we didn’t really listen to or question what we were being told. Had we asked more questions along the way, and had realistic expectations, we may not have been so shocked by the outcome. Moreover, we didn’t really question why the treatment may have failed during our follow-up consultation, and so entered into the second cycle with exactly the same protocols.

Related reading: Failed IVF cycles – Real Patient Cases

Don’t rush into anything

When IVF fails it can feel as though you are back at square one. The backup plan has failed, and it can feel like you’ve run out of options and there is no hope left.

Having probably spent many years trying to get pregnant naturally prior to attempting IVF treatment many people feel as though they need to move on without wasting more time. In order to feel as though they are doing something to get over the IVF failure many rush into decisions that are understandably poorly thought through.

Some will decide to close the door on IVF completely, and others leap straight into another cycle. In my experience, the immediate aftermath of a failed cycle is not the best time to make big decisions.

How to cope with IVF failures

We started our second IVF cycle barely three months after finding out that our first had failed. On reflection, this was far too soon. I hadn’t allowed nearly enough time for my head, my heart, or my body to heal properly. I wanted to stop the pain, the anger, and the feelings of despair, and the only solution I could see was to get pregnant as soon as possible.

In hindsight, there is no question in my mind that we should have taken a longer break to ensure that we were both in optimum condition, both physically and mentally, to withstand another cycle, but we were desperate to do something to alleviate the anguish and get out of that dreadful limbo.

The second IVF cycle was easier in some respects since we were no longer dealing with the unknown. However, we both found it more physically demanding, possibly because we were still so exhausted from the first cycle. Sadly, this cycle was also unsuccessful and ended in an early miscarriage.

You should also know how to establish and understand your personal boundaries regarding IVF treatment which may help you to make informed decisions about your further treatment.

Try to focus on what worked

Even if the ultimate outcome is negative, there will probably be plenty of aspects of the cycle that did go well. Try to focus on these as much as possible, especially if considering another IVF cycle in future.

Following our second cycle, I was continuously told by family and friends that I should focus on the fact that at least I could get pregnant. Initially, these comments infuriated me, as it felt as though no one really understood just how much we had invested to make it as far as a positive pregnancy test.

Acknowledging the short-lived pregnancy as a positive thing seemed futile. I couldn’t even contemplate the thought of trying IVF ever again – the pain was just too unbearable.

However, over time I started to realize that those people were right – there were positives to focus on, and I tried to gain strength from them. My body had reacted badly to the overstimulation which may have compromised the egg quality, but this could be adjusted in a subsequent cycle, and although we had suffered a miscarriage one in four pregnancies end this way, regardless of whether IVF was used or not. As bleak as things were, we had to acknowledge that there was still hope.

How To Cope With IVF Failures - What Happens To Your Body?
Take an IVF break

Take an IVF break

In the aftermath of an unsuccessful cycle, it is important to try and take as much time out to grieve and heal as you possibly can. If you haven’t taken time off work during treatment, then you should try and take some time out afterwards.

Many people I have spoken to found that, although they had felt unable to talk to their employer about treatment while they were going through it when a cycle failed, they found that they had no choice; going to work and putting on a brave face was impossible. They were grieving and needed time to mourn and come to terms with their loss before attempting to resume a normal life.

How To Cope With IVF Failures - What Happens To Your Body? 2
Find a new distraction

Find a new distraction

After months of researching treatment options, preparing body (nutrients and supplements if necessary) and mind, administering fertility drugs, adjusting hormone levels, ensuring your endometrium is as healthy as it can be, not to mention constant appointments and tests at a fertility clinic, IVF may have started to feel like a full-time job.

When it is over many people find themselves at a loose end. Without the joy of a pregnancy on which to focus, life can seem very empty all of a sudden, thus exacerbating the pain. If you feel up to it, try to find something entirely unrelated with which to distract yourself, such as a new activity or hobby.

What really helped me was to make a list of all the things I wanted to achieve in my life, whether I had children or not. It was essentially a bucket list that included all manner of activities, both big and small.

I started by ticking off the small things: eating in a restaurant I had always wanted to try and go to a museum I wanted to visit. The act of achieving a goal, no matter how small, and being able to tick something off my list made me feel stronger and more empowered.

Consider your treatment options

Before plunging ahead with a similar treatment plan, convincing yourself it was just bad luck that the first one failed, or before rejecting a new treatment plan that may seem extreme, spend time researching as much as you can. Many people make uninformed decisions about treatment only to regret it afterwards.

Talking openly to your physician and to other patients who have been in your shoes who might provide a new perspective. Ask about endometrial receptivity, scar tissue and other factors that could be impeding your fertility treatment. I have talked to many people who eventually became parents through a treatment option that they had initially rejected, so try not to close any doors before you have fully considered the options.

Some patients think about going for an IVF abroad and they do consult doctors from an overseas IVF clinics even though finally they stay at the home-based clinic. Having “a second opinion” might be a good choice.

Some patients think about changing the IVF clinic once they experienced IVF failure. Read our guide written by Professor Alan Thornhill on how to choose the right clinic for IVF treatment.

Maybe it’s time for some Fertility Counselling?

Just as counselling can offer invaluable help to patients who rely on assisted reproduction technology before and during treatment, it can also offer support when it fails.

A number of people who have experienced treatment failure told me that they gained huge strength from attending counselling sessions. Counselling will be particularly helpful for those who are unsure of whether to pursue further treatment or not.

Look after your relationship

A failed IVF cycle can take a huge toll on those who are in relationships. Like all forms of grief, the way each individual deals with the loss may be very different; this can lead to tension and even feelings of resentment between a couple.

Having gone through a third cycle I can understand why so many relationships do not survive IVF failure. Day-to-day living whilst going through the process becomes extremely strained and the relationship itself can become less important than the goal of having a baby.
Difficult as it may be, try to spend time talking and understanding each other’s grief, and continue to make time for yourselves as a couple.

The above extract is taken from Five Million Born – An IVF Companion Guide by Anne-Marie Scully. The guide is available at amazon.

Final Thoughts

Two stand out conclusions come from this thought provoking article. Namely, that whilst fertility treatment can be tough, extremely tough, you can get through it by carefully considering your options. Take time to talk to people, you physician, other patients, identify options which are higher risk and eliminate these if possible.

Secondly, there are also positives to be had. Try to focus on those aspects of the fertility treatment and experience that worked well. It may be that you now understand your body more; you recognise its potential; it may be that the treatment experience has brought you and your loved ones closer together. If you feel you are focussing too much on the negative aspects of the ivf attempt, try a distraction – do something completely alien to fertility treatment like refreshing or undertaking a hobby or pastime. Consider seeking the independent assistance of a counsellor if you feel that would help.

Above all, remember, however many cycles you undergo, it is ultimately your decision how far you want to take your own journey. The most important thing is that you do so relaxed, informed and in your own time.

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Editorial Team
Fertility Road aims to inform and inspire in a manner which is honest, direct and empathetic. Our worldwide expert writers break down the science and deliver relevant, up-to-date insights into everything related to IVF.

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